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Differential Effects of STCH and Stress-Inducible Hsp70 on the Stability and Maturation of NKCC2
Mutations in the Na-K-2Cl co-transporter NKCC2 lead to type I Bartter syndrome, a life-threatening kidney disease. We previously showed that export from the ER constitutes the limiting step in NKCC2 maturation and cell surface expression. Yet, the molecular mechanisms involved in this process remain...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926544/ https://www.ncbi.nlm.nih.gov/pubmed/33672238 http://dx.doi.org/10.3390/ijms22042207 |