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Cysteine [2,4] Disulfide Bond as a New Modifiable Site of α-Conotoxin TxIB

α-Conotoxin TxIB, a selective antagonist of α6/α3β2β3 nicotinic acetylcholine receptor, could be a potential therapeutic agent for addiction and Parkinson’s disease. As a peptide with a complex pharmacophoric conformation, it is important and difficult to find a modifiable site which can be modified...

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Detalles Bibliográficos
Autores principales: Zhang, Baojian, Ren, Maomao, Xiong, Yang, Li, Haonan, Wu, Yong, Fu, Ying, Zhangsun, Dongting, Dong, Shuai, Luo, Sulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926623/
https://www.ncbi.nlm.nih.gov/pubmed/33671487
http://dx.doi.org/10.3390/md19020119