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mTOR Signaling in Pulmonary Vascular Disease: Pathogenic Role and Therapeutic Target
Pulmonary arterial hypertension (PAH) is a progressive and fatal disease without a cure. The exact pathogenic mechanisms of PAH are complex and poorly understood, yet a number of abnormally expressed genes and regulatory pathways contribute to sustained vasoconstriction and vascular remodeling of th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926633/ https://www.ncbi.nlm.nih.gov/pubmed/33670032 http://dx.doi.org/10.3390/ijms22042144 |