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mTOR Signaling in Pulmonary Vascular Disease: Pathogenic Role and Therapeutic Target

Pulmonary arterial hypertension (PAH) is a progressive and fatal disease without a cure. The exact pathogenic mechanisms of PAH are complex and poorly understood, yet a number of abnormally expressed genes and regulatory pathways contribute to sustained vasoconstriction and vascular remodeling of th...

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Detalles Bibliográficos
Autores principales: Babicheva, Aleksandra, Makino, Ayako, Yuan, Jason X.-J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926633/
https://www.ncbi.nlm.nih.gov/pubmed/33670032
http://dx.doi.org/10.3390/ijms22042144