Synthesis, Neuroprotection, and Antioxidant Activity of 1,1′-Biphenylnitrones as α-Phenyl-N-tert-butylnitrone Analogues in In Vitro Ischemia Models

Herein, we report the neuroprotective and antioxidant activity of 1,1′-biphenyl nitrones (BPNs) 1–5 as α-phenyl-N-tert-butylnitrone analogues prepared from commercially available [1,1′-biphenyl]-4-carbaldehyde and [1,1′-biphenyl]-4,4′-dicarbaldehyde. The neuroprotection of BPNs 1-5 has been measured...

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Detalles Bibliográficos
Autores principales: Chamorro, Beatriz, García-Vieira, David, Diez-Iriepa, Daniel, Garagarza, Estíbaliz, Chioua, Mourad, Hadjipavlou-Litina, Dimitra, López-Muñoz, Francisco, Marco-Contelles, José, Oset-Gasque, María Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926640/
https://www.ncbi.nlm.nih.gov/pubmed/33672652
http://dx.doi.org/10.3390/molecules26041127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926640/
https://www.ncbi.nlm.nih.gov/pubmed/33672652
http://dx.doi.org/10.3390/molecules26041127

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