Regulation of Glucose Metabolism by MuRF1 and Treatment of Myopathy in Diabetic Mice with Small Molecules Targeting MuRF1

The muscle-specific ubiquitin ligase MuRF1 regulates muscle catabolism during chronic wasting states, although its roles in general metabolism are less-studied. Here, we metabolically profiled MuRF1-deficient knockout mice. We also included knockout mice for MuRF2 as its closely related gene homolog...

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Detalles Bibliográficos
Autores principales: Labeit, Siegfried, Hirner, Stephanie, Bogomolovas, Julijus, Cruz, André, Myrzabekova, Moldir, Moriscot, Anselmo, Bowen, Thomas Scott, Adams, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926706/
https://www.ncbi.nlm.nih.gov/pubmed/33672385
http://dx.doi.org/10.3390/ijms22042225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926706/
https://www.ncbi.nlm.nih.gov/pubmed/33672385
http://dx.doi.org/10.3390/ijms22042225

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