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Synthesis and Biological Evaluation of Novel 4-(4-Formamidophenylamino)-N-methylpicolinamide Derivatives as Potential Antitumor Agents

A novel series of 4-(4-formamidophenylamino)-N-methylpicolinamide derivatives were synthesized and evaluated against different tumor cell lines. Experiments in vitro showed that these derivatives could inhibit the proliferation of two kinds of human cancer cell lines (HepG2, HCT116) at low micromola...

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Detalles Bibliográficos
Autores principales: Meng, Nana, Zhou, Shuyan, Hu, Min, Xu, Youzhi, Xia, Yong, Zeng, Xiuxiu, Yu, Luoting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926825/
https://www.ncbi.nlm.nih.gov/pubmed/33670007
http://dx.doi.org/10.3390/molecules26041150