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Amelioration of Metal-Induced Cellular Stress by α-Lipoic Acid and Dihydrolipoic Acid through Antioxidative Effects in PC12 Cells and Caco-2 Cells

α-Lipoic acid (ALA) and its reduced form dihydrolipoic acid (DHLA) are endogenous dithiol compounds with significant antioxidant properties, both of which have the potential to detoxify cells. In this study, ALA (250 μM) and DHLA (50 μM) were applied to reduce metal (As, Cd, and Pb)-induced toxicity...

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Detalles Bibliográficos
Autores principales: Hossain, Kaniz Fatima Binte, Akter, Mahmuda, Rahman, Md. Mostafizur, Sikder, Md. Tajuddin, Rahaman, Md. Shiblur, Yamasaki, Shojiro, Kimura, Goh, Tomihara, Tomomi, Kurasaki, Masaaki, Saito, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926869/
https://www.ncbi.nlm.nih.gov/pubmed/33671655
http://dx.doi.org/10.3390/ijerph18042126