Cuprizone-Induced Neurotoxicity in Human Neural Cell Lines Is Mediated by a Reversible Mitochondrial Dysfunction: Relevance for Demyelination Models

Suitable in vivo and in vitro models are instrumental for the development of new drugs aimed at improving symptoms or progression of multiple sclerosis (MS). The cuprizone (CPZ)-induced murine model has gained momentum in recent decades, aiming to address the demyelination component of the disease....

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Detalles Bibliográficos
Autores principales: Martínez-Pinilla, Eva, Rubio-Sardón, Núria, Villar-Conde, Sandra, Navarro, Gemma, del Valle, Eva, Tolivia, Jorge, Franco, Rafael, Navarro, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926891/
https://www.ncbi.nlm.nih.gov/pubmed/33671675
http://dx.doi.org/10.3390/brainsci11020272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926891/
https://www.ncbi.nlm.nih.gov/pubmed/33671675
http://dx.doi.org/10.3390/brainsci11020272

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