Suramin Targets the Conserved Ligand-Binding Pocket of Human Raf1 Kinase Inhibitory Protein

Suramin was initially used to treat African sleeping sickness and has been clinically tested to treat human cancers and HIV infection in the recent years. However, the therapeutic index is low with numerous clinical side-effects, attributed to its diverse interactions with multiple biological macrom...

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Detalles Bibliográficos
Autores principales: Guo, Chenyun, Wu, Zhihua, Lin, Weiliang, Xu, Hao, Chang, Ting, Dai, Yazhuang, Lin, Donghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926937/
https://www.ncbi.nlm.nih.gov/pubmed/33670019
http://dx.doi.org/10.3390/molecules26041151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926937/
https://www.ncbi.nlm.nih.gov/pubmed/33670019
http://dx.doi.org/10.3390/molecules26041151

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