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Inhibition of the Sodium Calcium Exchanger Suppresses Alcohol Withdrawal-Induced Seizure Susceptibility

Calcium influx plays important roles in the pathophysiology of seizures, including acoustically evoked alcohol withdrawal-induced seizures (AWSs). One Ca(2+) influx route of interest is the Na(+)/Ca(2+) exchanger (NCX) that, when operating in its reverse mode (NCX(rev)) activity, can facilitate Ca(2...

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Detalles Bibliográficos
Autores principales: Newton, Jamila, Akinfiresoye, Luli Rebecca, N’Gouemo, Prosper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926990/
https://www.ncbi.nlm.nih.gov/pubmed/33672412
http://dx.doi.org/10.3390/brainsci11020279