Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-Signaling

SIMPLE SUMMARY: The correct folding of proteins is essential for their activity. Therefore, cells have evolved protein-folding chaperones, such as Hsp90. Interestingly, in several cancer cells, Hsp90 appears to have a role that is more important than normal. The current working model suggests that,...

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Detalles Bibliográficos
Autores principales: Siddiqui, Farid Ahmad, Parkkola, Hanna, Vukic, Vladimir, Oetken-Lindholm, Christina, Jaiswal, Alok, Kiriazis, Alexandros, Pavic, Karolina, Aittokallio, Tero, Salminen, Tiina A., Abankwa, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927014/
https://www.ncbi.nlm.nih.gov/pubmed/33672199
http://dx.doi.org/10.3390/cancers13040927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927014/
https://www.ncbi.nlm.nih.gov/pubmed/33672199
http://dx.doi.org/10.3390/cancers13040927

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