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Hyperglycemia Potentiates Prothrombotic Effect of Aldosterone in a Rat Arterial Thrombosis Model

We investigated the role of aldosterone (ALDO) in the development of arterial thrombosis in streptozotocin-induced diabetic rats. To evaluate the effect of endogenous ALDO, the rats underwent adrenalectomy (ADX). ADX reduced the development of arterial thrombosis. A 1 h infusion of ALDO (30 μg/kg/h)...

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Detalles Bibliográficos
Autores principales: Gromotowicz-Poplawska, Anna, Szoka, Piotr, Zakrzeska, Agnieszka, Kolodziejczyk, Patrycjusz, Marcinczyk, Natalia, Szemraj, Janusz, Tutka, Piotr, Chabielska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927020/
https://www.ncbi.nlm.nih.gov/pubmed/33671798
http://dx.doi.org/10.3390/cells10020471