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Insufficient Stability of Clavulanic Acid in Widely Used Child-Appropriate Formulations

Amoxicillin-clavulanic acid (AMC) belongs to the WHO Essential Medicines List for children, but for optimal antimicrobial effectiveness, reconstituted dry powder suspensions need to be stored in a refrigerated environment. Many patients in low- and middle-income countries who are sold AMC suspension...

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Detalles Bibliográficos
Autores principales: Mack, Ines, Sharland, Mike, Brussee, Janneke M., Rehm, Sophia, Rentsch, Katharina, Bielicki, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927114/
https://www.ncbi.nlm.nih.gov/pubmed/33672363
http://dx.doi.org/10.3390/antibiotics10020225