Relevance of Electrostatics for the Interaction of Tyrosine Hydroxylase with Porous Silicon Nanoparticles

[Image: see text] Tyrosine hydroxylase (TH) is the enzyme catalyzing the rate-limiting step in the synthesis of dopamine in the brain. Developing enzyme replacement therapies using TH could therefore be beneficial to patient groups with dopamine deficiency, and the use of nanocarriers that cross the...

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Detalles Bibliográficos
Autores principales: Bezem, Maria T., Johannessen, Fredrik G., Kråkenes, Trond-André, Sailor, Michael J., Martinez, Aurora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927144/
https://www.ncbi.nlm.nih.gov/pubmed/33417459
http://dx.doi.org/10.1021/acs.molpharmaceut.0c00960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927144/
https://www.ncbi.nlm.nih.gov/pubmed/33417459
http://dx.doi.org/10.1021/acs.molpharmaceut.0c00960

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