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Growth disadvantage associated with centrosome amplification drives population-level centriole number homeostasis
The centriole duplication cycle normally ensures that centriole number is maintained at two centrioles per G1 cell. However, some circumstances can result in an aberrant increase in centriole number—a phenotype that is particularly prevalent in several types of cancer. Following an artificial increa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927180/ https://www.ncbi.nlm.nih.gov/pubmed/32966175 http://dx.doi.org/10.1091/mbc.E19-04-0195 |