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Growth disadvantage associated with centrosome amplification drives population-level centriole number homeostasis

The centriole duplication cycle normally ensures that centriole number is maintained at two centrioles per G1 cell. However, some circumstances can result in an aberrant increase in centriole number—a phenotype that is particularly prevalent in several types of cancer. Following an artificial increa...

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Detalles Bibliográficos
Autores principales: Sala, Roberta, Farrell, KC, Stearns, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927180/
https://www.ncbi.nlm.nih.gov/pubmed/32966175
http://dx.doi.org/10.1091/mbc.E19-04-0195