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Ase1 domains dynamically slow anaphase spindle elongation and recruit Bim1 to the midzone

How cells regulate microtubule cross-linking activity to control the rate and duration of spindle elongation during anaphase is poorly understood. In this study, we test the hypothesis that PRC1/Ase1 proteins use distinct microtubule-binding domains to control the spindle elongation rate. Using the...

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Detalles Bibliográficos
Autores principales: Thomas, Ezekiel C., Ismael, Amber, Moore, Jeffrey K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927185/
https://www.ncbi.nlm.nih.gov/pubmed/32997572
http://dx.doi.org/10.1091/mbc.E20-07-0493-T