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Direct involvement of Hsp70 ATP hydrolysis in Ubr1-dependent quality control

Chaperones can mediate both protein folding and degradation. This process is referred to as protein triage, which demands study to reveal mechanisms of quality control for both basic scientific and translational purposes. In yeast, many misfolded proteins undergo chaperone-dependent ubiquitination b...

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Detalles Bibliográficos
Autores principales: Singh, Amanjot, Vashistha, Nidhi, Heck, Jarrod, Tang, Xin, Wipf, Peter, Brodsky, Jeffrey L., Hampton, Randolph Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927186/
https://www.ncbi.nlm.nih.gov/pubmed/32966159
http://dx.doi.org/10.1091/mbc.E20-08-0541