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Direct involvement of Hsp70 ATP hydrolysis in Ubr1-dependent quality control
Chaperones can mediate both protein folding and degradation. This process is referred to as protein triage, which demands study to reveal mechanisms of quality control for both basic scientific and translational purposes. In yeast, many misfolded proteins undergo chaperone-dependent ubiquitination b...
Autores principales: | Singh, Amanjot, Vashistha, Nidhi, Heck, Jarrod, Tang, Xin, Wipf, Peter, Brodsky, Jeffrey L., Hampton, Randolph Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927186/ https://www.ncbi.nlm.nih.gov/pubmed/32966159 http://dx.doi.org/10.1091/mbc.E20-08-0541 |
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