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Genomic alterations in KMT2 family predict outcome of immune checkpoint therapy in multiple cancers

Immune checkpoint therapy (ICT) can produce durable antitumor responses in various cancer types; however, the responses are not universal, and the predictive biomarkers are urgently needed. Growing evidence points to a link between epigenetic regulation and anti-tumor immunity, while clinical data o...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Huang, Yixuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927217/
https://www.ncbi.nlm.nih.gov/pubmed/33653367
http://dx.doi.org/10.1186/s13045-021-01050-0