Improving l-threonine production in Escherichia coli by elimination of transporters ProP and ProVWX

BACKGROUND: Betaine, an osmoprotective compatible solute, has been used to improve l-threonine production in engineered Escherichia coli l-threonine producer. Betaine supplementation upregulates the expression of zwf encoding glucose-6-phosphate dehydrogenase, leading to the increase of NADPH, which...

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Detalles Bibliográficos
Autores principales: Wang, Shuaiwen, Fang, Yu, Wang, Zhen, Zhang, Shuyan, Wang, Liangjia, Guo, Yong, Wang, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927397/
https://www.ncbi.nlm.nih.gov/pubmed/33653345
http://dx.doi.org/10.1186/s12934-021-01546-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927397/
https://www.ncbi.nlm.nih.gov/pubmed/33653345
http://dx.doi.org/10.1186/s12934-021-01546-x

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