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Improving l-threonine production in Escherichia coli by elimination of transporters ProP and ProVWX
BACKGROUND: Betaine, an osmoprotective compatible solute, has been used to improve l-threonine production in engineered Escherichia coli l-threonine producer. Betaine supplementation upregulates the expression of zwf encoding glucose-6-phosphate dehydrogenase, leading to the increase of NADPH, which...
Autores principales: | Wang, Shuaiwen, Fang, Yu, Wang, Zhen, Zhang, Shuyan, Wang, Liangjia, Guo, Yong, Wang, Xiaoyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927397/ https://www.ncbi.nlm.nih.gov/pubmed/33653345 http://dx.doi.org/10.1186/s12934-021-01546-x |
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