Intact Glucocorticoid Receptor Dimerization Is Deleterious in Trauma-Induced Impaired Fracture Healing

Following severe trauma, fracture healing is impaired because of overwhelming systemic and local inflammation. Glucocorticoids (GCs), acting via the glucocorticoid receptor (GR), influence fracture healing by modulating the trauma-induced immune response. GR dimerization-dependent gene regulation is...

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Detalles Bibliográficos
Autores principales: Hachemi, Yasmine, Rapp, Anna E., Lee, Sooyeon, Dorn, Ann-Kristin, Krüger, Benjamin T., Kaiser, Kathrin, Ignatius, Anita, Tuckermann, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927427/
https://www.ncbi.nlm.nih.gov/pubmed/33679723
http://dx.doi.org/10.3389/fimmu.2020.628287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927427/
https://www.ncbi.nlm.nih.gov/pubmed/33679723
http://dx.doi.org/10.3389/fimmu.2020.628287

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