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Reversible Treatment of Pressure Overload‐Induced Left Ventricular Hypertrophy through Drd5 Nucleic Acid Delivery Mediated by Functional Polyaminoglycoside

Left ventricular hypertrophy and fibrosis are major risk factors for heart failure, which require timely and effective treatment. Genetic therapy has been shown to ameliorate hypertrophic cardiac damage. In this study, it is found that in mice, the dopamine D5 receptor (D5R) expression in the left v...

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Detalles Bibliográficos
Autores principales: Jiang, Xiaoliang, Shao, Meiyu, Liu, Xue, Liu, Xing, Zhang, Xu, Wang, Yuming, Yin, Kunlun, Wang, Shuiyun, Hu, Yang, Jose, Pedro A, Zhou, Zhou, Xu, Fu‐Jian, Yang, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927605/
https://www.ncbi.nlm.nih.gov/pubmed/33717857
http://dx.doi.org/10.1002/advs.202003706