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TAK1 Phosphorylates RASSF9 and Inhibits Esophageal Squamous Tumor Cell Proliferation by Targeting the RAS/MEK/ERK Axis

TGF‐β‐activated kinase 1 (TAK1), a serine/threonine kinase, is a key intermediate in several signaling pathways. However, its role in tumorigenesis is still not understood well. In this study, it is found that TAK1 expression decreases in esophageal tumor tissues and cell lines. In vitro experiments...

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Detalles Bibliográficos
Autores principales: Shi, Hui, Ju, Qianqian, Mao, Yinting, Wang, Yuejun, Ding, Jie, Liu, Xiaoyu, Tang, Xin, Sun, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927628/
https://www.ncbi.nlm.nih.gov/pubmed/33717835
http://dx.doi.org/10.1002/advs.202001575