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Fast inactivation of Nav current in rat adrenal chromaffin cells involves two independent inactivation pathways

Voltage-dependent sodium (Nav) current in adrenal chromaffin cells (CCs) is rapidly inactivating and tetrodotoxin (TTX)–sensitive. The fractional availability of CC Nav current has been implicated in regulation of action potential (AP) frequency and the occurrence of slow-wave burst firing. Here, th...

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Detalles Bibliográficos
Autores principales: Martinez-Espinosa, Pedro L., Neely, Alan, Ding, Jiuping, Lingle, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927663/
https://www.ncbi.nlm.nih.gov/pubmed/33647101
http://dx.doi.org/10.1085/jgp.202012784