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Surface‐bound matrix metalloproteinase‐8 on macrophages: Contributions to macrophage pericellular proteolysis and migration through tissue barriers

OBJECTIVE: MMP‐8 binds to surface‐bound tissue inhibitor of metalloproteinase‐1 (TIMP‐1) on PMNs to promote pericellular proteolysis during the development of inflammatory diseases associated with tissue destruction. Little is known about the biology of MMP‐8 in macrophages. We tested the hypotheses...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyun, Zhang, Duo, Fucci, Quynh‐Anh, Dollery, Clare M., Owen, Caroline A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927794/
https://www.ncbi.nlm.nih.gov/pubmed/33656791
http://dx.doi.org/10.14814/phy2.14778