In Vitro Exposure of Leukocytes to HIV Preexposure Prophylaxis Decreases Mitochondrial Function and Alters Gene Expression Profiles

The use of antiretroviral therapy (ART) as preexposure prophylaxis (PrEP) is an effective strategy for preventing HIV acquisition. The cellular consequences of PrEP exposure, however, have not been sufficiently explored to determine potential effects on health in individuals without HIV. In this stu...

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Detalles Bibliográficos
Autores principales: Bowman, Emily R., Cameron, Cheryl, Richardson, Brian, Kulkarni, Manjusha, Gabriel, Janelle, Kettelhut, Aaren, Hornsby, Lane, Kwiek, Jesse J., Turner, Abigail Norris, Malvestutto, Carlos, Bazan, Jose, Koletar, Susan L., Doblecki-Lewis, Susanne, Lederman, Michael M., Cameron, Mark, Klatt, Nichole R., Lake, Jordan E., Funderburg, Nicholas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927818/
https://www.ncbi.nlm.nih.gov/pubmed/33020165
http://dx.doi.org/10.1128/AAC.01755-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927818/
https://www.ncbi.nlm.nih.gov/pubmed/33020165
http://dx.doi.org/10.1128/AAC.01755-20

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