Development of a Simple In Vitro Assay To Identify and Evaluate Nucleotide Analogs against SARS-CoV-2 RNA-Dependent RNA Polymerase

Nucleotide analogs targeting viral RNA polymerase have been proved to be an effective strategy for antiviral treatment and are promising antiviral drugs to combat the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. In this study, we developed a robust in vitro nonradio...

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Detalles Bibliográficos
Autores principales: Lu, Gaofei, Zhang, Xi, Zheng, Weinan, Sun, Jialei, Hua, Lan, Xu, Lan, Chu, Xin-jie, Ding, Sheng, Xiong, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927875/
https://www.ncbi.nlm.nih.gov/pubmed/33122171
http://dx.doi.org/10.1128/AAC.01508-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927875/
https://www.ncbi.nlm.nih.gov/pubmed/33122171
http://dx.doi.org/10.1128/AAC.01508-20

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