NGN2 mmRNA-Based Transcriptional Programming in Microfluidic Guides hiPSCs Toward Neural Fate With Multiple Identities

Recent advancements in cell engineering have succeeded in manipulating cell identity with the targeted overexpression of specific cell fate determining transcription factors in a process named transcriptional programming. Neurogenin2 (NGN2) is sufficient to instruct pluripotent stem cells (PSCs) to...

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Detalles Bibliográficos
Autores principales: Tolomeo, Anna Maria, Laterza, Cecilia, Grespan, Eleonora, Michielin, Federica, Canals, Isaac, Kokaia, Zaal, Muraca, Maurizio, Gagliano, Onelia, Elvassore, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928329/
https://www.ncbi.nlm.nih.gov/pubmed/33679325
http://dx.doi.org/10.3389/fncel.2021.602888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928329/
https://www.ncbi.nlm.nih.gov/pubmed/33679325
http://dx.doi.org/10.3389/fncel.2021.602888

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