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NGN2 mmRNA-Based Transcriptional Programming in Microfluidic Guides hiPSCs Toward Neural Fate With Multiple Identities
Recent advancements in cell engineering have succeeded in manipulating cell identity with the targeted overexpression of specific cell fate determining transcription factors in a process named transcriptional programming. Neurogenin2 (NGN2) is sufficient to instruct pluripotent stem cells (PSCs) to...
Autores principales: | Tolomeo, Anna Maria, Laterza, Cecilia, Grespan, Eleonora, Michielin, Federica, Canals, Isaac, Kokaia, Zaal, Muraca, Maurizio, Gagliano, Onelia, Elvassore, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928329/ https://www.ncbi.nlm.nih.gov/pubmed/33679325 http://dx.doi.org/10.3389/fncel.2021.602888 |
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