Cargando…

NGN2 mmRNA-Based Transcriptional Programming in Microfluidic Guides hiPSCs Toward Neural Fate With Multiple Identities

Recent advancements in cell engineering have succeeded in manipulating cell identity with the targeted overexpression of specific cell fate determining transcription factors in a process named transcriptional programming. Neurogenin2 (NGN2) is sufficient to instruct pluripotent stem cells (PSCs) to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tolomeo, Anna Maria, Laterza, Cecilia, Grespan, Eleonora, Michielin, Federica, Canals, Isaac, Kokaia, Zaal, Muraca, Maurizio, Gagliano, Onelia, Elvassore, Nicola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928329/ https://www.ncbi.nlm.nih.gov/pubmed/33679325 http://dx.doi.org/10.3389/fncel.2021.602888

Ejemplares similares

Dopaminergic differentiation of schizophrenia hiPSCs
por: Hartley, Brigham J., et al.
Publicado: (2015)

Genetic Cardiomyopathies: The Lesson Learned from hiPSCs
por: My, Ilaria, et al.
Publicado: (2021)

The Microfluidic Environment Reveals a Hidden Role of Self-Organizing Extracellular Matrix in Hepatic Commitment and Organoid Formation of hiPSCs
por: Michielin, Federica, et al.
Publicado: (2020)

Generation of hiPSC-Derived Skeletal Muscle Cells: Exploiting the Potential of Skeletal Muscle-Derived hiPSCs
por: Metzler, Eric, et al.
Publicado: (2022)

Fluorescent Gene Tagging of Transcriptionally Silent Genes in hiPSCs
por: Roberts, Brock, et al.
Publicado: (2019)

hiPSCs for predictive modelling of neurodegenerative diseases: dreaming the possible
por: Rivetti di Val Cervo, Pia, et al.
Publicado: (2021)

Fabrication of functional ameloblasts from hiPSCs for dental application
por: Kim, Ka-Hwa, et al.
Publicado: (2023)

Reprogramming of HUVECs into Induced Pluripotent Stem Cells (HiPSCs), Generation and Characterization of HiPSC-Derived Neurons and Astrocytes
por: Haile, Yohannes, et al.
Publicado: (2015)

Human Pluripotent Stem Cell-Derived Micropatterned Ectoderm Allows Cell Sorting of Meso-Endoderm Lineages
por: Yang, Yang, et al.
Publicado: (2022)

ASSURED-optimized CRISPR protocol for knockout/SNP knockin in hiPSCs
por: Ludwik, Katarzyna A., et al.
Publicado: (2023)

Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons
por: Li, Aiqun, et al.
Publicado: (2021)

Combining NGN2 programming and dopaminergic patterning for a rapid and efficient generation of hiPSC-derived midbrain neurons
por: Sheta, Razan, et al.
Publicado: (2022)

Experimental Models to Study Autism Spectrum Disorders: hiPSCs, Rodents and Zebrafish
por: Pensado-López, Alba, et al.
Publicado: (2020)

Biomaterials and Advanced Biofabrication Techniques in hiPSCs Based Neuromyopathic Disease Modeling
por: Sun, Jing, et al.
Publicado: (2019)

Applying hiPSCs and Biomaterials Towards an Understanding and Treatment of Traumatic Brain Injury
por: Lacalle-Aurioles, María, et al.
Publicado: (2020)

PCSK9 regulates the NODAL signaling pathway and cellular proliferation in hiPSCs
por: Roudaut, Meryl, et al.
Publicado: (2021)

GCT-19. MODELING GERM CELL TUMORS WITH KIT MUTANT hiPSCs
por: Kuzuoka, Sakura, et al.
Publicado: (2020)

Timely delivery of cardiac mmRNAs in microfluidics enhances cardiogenic programming of human pluripotent stem cells
por: Contato, Anna, et al.
Publicado: (2022)

Integrating Oxygen and 3D Cell Culture System: A Simple Tool to Elucidate the Cell Fate Decision of hiPSCs
por: Khadim, Rubina Rahaman, et al.
Publicado: (2022)

Long-term calcium imaging reveals functional development in hiPSC-derived cultures comparable to human but not rat primary cultures
por: Estévez-Priego, Estefanía, et al.
Publicado: (2022)

Generation and Neuronal Differentiation of hiPSCs From Patients With Myotonic Dystrophy Type 2
por: Spitalieri, Paola, et al.
Publicado: (2018)

Differentiation and Functional Comparison of Monocytes and Macrophages from hiPSCs with Peripheral Blood Derivatives
por: Cao, Xu, et al.
Publicado: (2019)

GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm
por: Sharma, Arun, et al.
Publicado: (2020)

Effects of Simulated Microgravity on Wild Type and Marfan hiPSCs-Derived Embryoid Bodies
por: Spitalieri, Paola, et al.
Publicado: (2021)

Microvessels derived from hiPSCs are a novel source for angiogenesis and tissue regeneration
por: Gao, Xin, et al.
Publicado: (2022)

Xeno-Free Integrated Platform for Robust Production of Cardiomyocyte Sheets from hiPSCs
por: Dias, Tiago P., et al.
Publicado: (2022)

Generation of hiPSCs with ABO c.767T>C substitution: resulting in splicing variants
por: Jin, Yinge, et al.
Publicado: (2023)

Analysis of protein coding mutations in hiPSCs and their possible role during somatic cell reprogramming
por: Ruiz, Sergio, et al.
Publicado: (2013)

FUS Mislocalization and Vulnerability to DNA Damage in ALS Patients Derived hiPSCs and Aging Motoneurons
por: Higelin, Julia, et al.
Publicado: (2016)

The Role of MicroRNAs in Early Chondrogenesis of Human Induced Pluripotent Stem Cells (hiPSCs)
por: Stelcer, Ewelina, et al.
Publicado: (2019)

PGC-1α promotes mitochondrial respiration and biogenesis during the differentiation of hiPSCs into cardiomyocytes
por: Zhou, Qin, et al.
Publicado: (2020)

Exploiting hiPSCs in Leber's Hereditary Optic Neuropathy (LHON): Present Achievements and Future Perspectives
por: Peron, Camille, et al.
Publicado: (2021)

Investigation of the hepatic development in the coculture of hiPSCs-derived LSECs and HLCs in a fluidic microenvironment
por: Danoy, Mathieu, et al.
Publicado: (2021)

CRISPR-Cas9 in hiPSCs: A new era in personalized treatment for Stargardt disease
por: Kuntam, Soujanya, et al.
Publicado: (2023)

Deepening the understanding of CNVs on chromosome 15q11–13 by using hiPSCs: An overview
por: Giovenale, Angela Maria Giada, et al.
Publicado: (2023)

mMRNA-1273: Autoimmune hepatitis: case report
Publicado: (2021)

Optimized Surface Markers for the Prospective Isolation of High-Quality hiPSCs using Flow Cytometry Selection
por: Abujarour, Ramzey, et al.
Publicado: (2013)

Platform for Induction and Maintenance of Transgene-free hiPSCs Resembling Ground State Pluripotent Stem Cells
por: Valamehr, Bahram, et al.
Publicado: (2014)

Reproducible and efficient generation of functionally active neurons from human hiPSCs for preclinical disease modeling
por: Xie, Yunyao, et al.
Publicado: (2017)

Comparison of multi-lineage differentiation of hiPSCs reveals novel miRNAs that regulate lineage specification
por: Li, Lu, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_vn0sninrcdhnr50gs47ioiodnr