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Ginkgolide B Maintains Calcium Homeostasis in Hypoxic Hippocampal Neurons by Inhibiting Calcium Influx and Intracellular Calcium Release

Ginkgolide B (GB), a terpene lactone and active ingredient of Ginkgo biloba, shows protective effects in neuronal cells subjected to hypoxia. We investigated whether GB might protect neurons from hypoxic injury through regulation of neuronal Ca(2+) homeostasis. Primary hippocampal neurons subjected...

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Detalles Bibliográficos
Autores principales: Wang, Li, Lei, Quan, Zhao, Shuai, Xu, WenJuan, Dong, Wei, Ran, JiHua, Shi, QingHai, Fu, JianFeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928385/
https://www.ncbi.nlm.nih.gov/pubmed/33679323
http://dx.doi.org/10.3389/fncel.2020.627846