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Improved in vitro Efficacy of Baloxavir Marboxil Against Influenza A Virus Infection by Combination Treatment With the MEK Inhibitor ATR-002

Currently, all available antiviral drugs against influenza virus (IV) that target the virus proteins directly, like Baloxavir acid (BXA), lead to viral resistance. Therefore, cellular mechanisms and factors essential for IV replication are promising antiviral targets. As IV strongly depends on the v...

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Detalles Bibliográficos
Autores principales: Hamza, Hazem, Shehata, Mahmoud M., Mostafa, Ahmed, Pleschka, Stephan, Planz, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928405/
https://www.ncbi.nlm.nih.gov/pubmed/33679636
http://dx.doi.org/10.3389/fmicb.2021.611958