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Knockdown of circRNA circ_0087378 Represses the Tumorigenesis and Progression of Esophageal Squamous Cell Carcinoma Through Modulating the miR-140-3p/E2F3 Axis

BACKGROUND: We aimed to investigate the function and underlying mechanisms of circ_0087378 in esophageal squamous cell carcinoma (ESCC). METHODS: We verified higher circ_0087378 expression in ESCC tissues by performing qRT-PCR assays. We further confirmed the oncogenic roles of circ_0087378 in ESCC...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Wang, Qiushuang, Gong, Yi, Hu, Qiu, Zhang, Haoliang, Ke, Shaobo, Chen, Yongshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928419/
https://www.ncbi.nlm.nih.gov/pubmed/33680929
http://dx.doi.org/10.3389/fonc.2020.607231