Cytoplasmic short linear motifs in ACE2 and integrin β(3) link SARS-CoV-2 host cell receptors to mediators of endocytosis and autophagy

The spike protein of SARS-CoV-2 binds the angiotensin-converting enzyme 2 (ACE2) on the host cell surface and subsequently enters host cells through receptor-mediated endocytosis. Additional cell receptors may be directly or indirectly involved, including integrins. The cytoplasmic tails of ACE2 and...

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Detalles Bibliográficos
Autores principales: Kliche, Johanna, Kuss, Hanna, Ali, Muhammad, Ivarsson, Ylva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928716/
https://www.ncbi.nlm.nih.gov/pubmed/33436498
http://dx.doi.org/10.1126/scisignal.abf1117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928716/
https://www.ncbi.nlm.nih.gov/pubmed/33436498
http://dx.doi.org/10.1126/scisignal.abf1117

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