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The Heterogeneous Landscape and Early Evolution of Pathogen-Associated CpG Dinucleotides in SARS-CoV-2

COVID-19 can lead to acute respiratory syndrome, which can be due to dysregulated immune signaling. We analyze the distribution of CpG dinucleotides, a pathogen-associated molecular pattern, in the SARS-CoV-2 genome. We characterize CpG content by a CpG force that accounts for statistical constraint...

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Detalles Bibliográficos
Autores principales: Di Gioacchino, Andrea, Šulc, Petr, Komarova, Anastassia V, Greenbaum, Benjamin D, Monasson, Rémi, Cocco, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928797/
https://www.ncbi.nlm.nih.gov/pubmed/33555346
http://dx.doi.org/10.1093/molbev/msab036