Integration of genetically regulated gene expression and pharmacological library provides therapeutic drug candidates

Approaches toward new therapeutics using disease genomics, such as genome-wide association study (GWAS), are anticipated. Here, we developed Trans-Phar [integration of transcriptome-wide association study (TWAS) and pharmacological database], achieving in silico screening of compounds from a large-s...

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Detalles Bibliográficos
Autores principales: Konuma, Takahiro, Ogawa, Kotaro, Okada, Yukinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Bioinformatics Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928862/
https://www.ncbi.nlm.nih.gov/pubmed/33577681
http://dx.doi.org/10.1093/hmg/ddab049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928862/
https://www.ncbi.nlm.nih.gov/pubmed/33577681
http://dx.doi.org/10.1093/hmg/ddab049

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