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Cathepsin D: A Candidate Link between Amyloid β-protein and Tauopathy in Alzheimer Disease

Alzheimer disease (AD) is a debilitating neurodegenerative disorder characterized by extracellular deposition of the amyloid β-protein (Aβ) and intraneuronal accumulation of the microtubule-associated protein, tau. Despite a wealth of experimental and genetic evidence implicating both Aβ and tau in...

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Detalles Bibliográficos
Autores principales: Suire, Caitlin N., Leissring, Malcolm A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929084/
https://www.ncbi.nlm.nih.gov/pubmed/33665647