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Dissecting phenotypic transitions in metastatic disease via photoconversion-based isolation

Cancer patients often harbor occult metastases, a potential source of relapse that is targetable only through systemic therapy. Studies of this occult fraction have been limited by a lack of tools with which to isolate discrete cells on spatial grounds. We developed PIC-IT, a photoconversion-based i...

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Detalles Bibliográficos
Autores principales: Sela, Yogev, Li, Jinyang, Kuri, Paola, Merrell, Allyson J, Li, Ning, Lengner, Chris, Rompolas, Pantelis, Stanger, Ben Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929558/
https://www.ncbi.nlm.nih.gov/pubmed/33620315
http://dx.doi.org/10.7554/eLife.63270