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Integrative pan cancer analysis reveals epigenomic variation in cancer type and cell specific chromatin domains
Epigenetic mechanisms contribute to the initiation and development of cancer, and epigenetic variation promotes dynamic gene expression patterns that facilitate tumor evolution and adaptation. While the NCI-60 panel represents a diverse set of human cancer cell lines that has been used to screen che...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930052/ https://www.ncbi.nlm.nih.gov/pubmed/33658503 http://dx.doi.org/10.1038/s41467-021-21707-1 |