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Integrative pan cancer analysis reveals epigenomic variation in cancer type and cell specific chromatin domains

Epigenetic mechanisms contribute to the initiation and development of cancer, and epigenetic variation promotes dynamic gene expression patterns that facilitate tumor evolution and adaptation. While the NCI-60 panel represents a diverse set of human cancer cell lines that has been used to screen che...

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Detalles Bibliográficos
Autores principales: Gopi, Lijin K., Kidder, Benjamin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930052/
https://www.ncbi.nlm.nih.gov/pubmed/33658503
http://dx.doi.org/10.1038/s41467-021-21707-1