Emerging Perspectives on Dipeptide Repeat Proteins in C9ORF72 ALS/FTD

The most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is a hexanucleotide expansion in the chromosome 9 open reading frame 72 gene (C9ORF72). This hexanucleotide expansion consists of GGGGCC (G(4)C(2)) repeats that have been implicated to lead to thre...

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Detalles Bibliográficos
Autores principales: Schmitz, Alexander, Pinheiro Marques, João, Oertig, Irina, Maharjan, Niran, Saxena, Smita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930069/
https://www.ncbi.nlm.nih.gov/pubmed/33679328
http://dx.doi.org/10.3389/fncel.2021.637548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930069/
https://www.ncbi.nlm.nih.gov/pubmed/33679328
http://dx.doi.org/10.3389/fncel.2021.637548

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