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The Role of β Cell Stress and Neo-Epitopes in the Immunopathology of Type 1 Diabetes
Due to their secretory function, β cells are predisposed to higher levels of endoplasmic reticulum (ER) stress and greater sensitivity to inflammation than other cell types. These stresses elicit changes in β cells that alter their function and immunogenicity, including defective ribosomal initiatio...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930070/ https://www.ncbi.nlm.nih.gov/pubmed/33679609 http://dx.doi.org/10.3389/fendo.2020.624590 |