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The Role of β Cell Stress and Neo-Epitopes in the Immunopathology of Type 1 Diabetes

Due to their secretory function, β cells are predisposed to higher levels of endoplasmic reticulum (ER) stress and greater sensitivity to inflammation than other cell types. These stresses elicit changes in β cells that alter their function and immunogenicity, including defective ribosomal initiatio...

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Detalles Bibliográficos
Autores principales:	Piganelli, Jon D., Mamula, Mark J., James, Eddie A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930070/ https://www.ncbi.nlm.nih.gov/pubmed/33679609 http://dx.doi.org/10.3389/fendo.2020.624590

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