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A scalable unified framework of total and allele-specific counts for cis-QTL, fine-mapping, and prediction

Genetic studies of the transcriptome help bridge the gap between genetic variation and phenotypes. To maximize the potential of such studies, efficient methods to identify expression quantitative trait loci (eQTLs) and perform fine-mapping and genetic prediction of gene expression traits are needed....

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Detalles Bibliográficos
Autores principales: Liang, Yanyu, Aguet, François, Barbeira, Alvaro N., Ardlie, Kristin, Im, Hae Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930098/
https://www.ncbi.nlm.nih.gov/pubmed/33658504
http://dx.doi.org/10.1038/s41467-021-21592-8