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Gene Expression Profiles Reveal Extracellular Matrix and Inflammatory Signaling in Radiation-Induced Premature Differentiation of Human Fibroblast in vitro

PURPOSE: Fibroblasts are considered to play a major role in the development of fibrotic reaction after radiotherapy and premature radiation-induced differentiation has been proposed as a cellular basis. The purpose was to relate gene expression profiles to radiation-induced phenotypic changes of hum...

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Detalles Bibliográficos
Autores principales: Herskind, Carsten, Sticht, Carsten, Sami, Ahmad, Giordano, Frank A., Wenz, Frederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930333/
https://www.ncbi.nlm.nih.gov/pubmed/33681189
http://dx.doi.org/10.3389/fcell.2021.539893