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In Vivo Priming of Peritoneal Tumor-Reactive Lymphocytes With a Potent Oncolytic Virus for Adoptive Cell Therapy

Adoptive cell therapy (ACT) using autologous tumor infiltrating lymphocytes (TIL) achieves durable clinical benefit for patients from whom these cells can be derived in advanced metastatic melanoma but is limited in most solid tumors as a result of immune escape and exclusion. A tumor microenvironme...

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Detalles Bibliográficos
Autores principales: Giehl, Esther, Kosaka, Hiromichi, Liu, Zuqiang, Feist, Mathilde, Kammula, Udai S., Lotze, Michael T., Ma, Congrong, Guo, Zong Sheng, Bartlett, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930493/
https://www.ncbi.nlm.nih.gov/pubmed/33679747
http://dx.doi.org/10.3389/fimmu.2021.610042