Ferroptosis Enhanced Diabetic Renal Tubular Injury via HIF-1α/HO-1 Pathway in db/db Mice

BACKGROUND: Ferroptosis is a recently identified iron-dependent form of cell death as a result of increased reactive oxygen species (ROS) and lipid peroxidation. In this study, we investigated whether ferroptosis aggravated diabetic nephropathy (DN) and damaged renal tubules through hypoxia-inducibl...

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Detalles Bibliográficos
Autores principales: Feng, Xiaomeng, Wang, Shuo, Sun, Zhencheng, Dong, Hengbei, Yu, Haitian, Huang, Mengxiu, Gao, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930496/
https://www.ncbi.nlm.nih.gov/pubmed/33679620
http://dx.doi.org/10.3389/fendo.2021.626390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930496/
https://www.ncbi.nlm.nih.gov/pubmed/33679620
http://dx.doi.org/10.3389/fendo.2021.626390

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