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The Interplay Between Tumor Suppressor p53 and Hypoxia Signaling Pathways in Cancer

Hypoxia is a hallmark of solid tumors and plays a critical role in different steps of tumor progression, including proliferation, survival, angiogenesis, metastasis, metabolic reprogramming, and stemness of cancer cells. Activation of the hypoxia-inducible factor (HIF) signaling plays a critical rol...

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Detalles Bibliográficos
Autores principales: Zhang, Cen, Liu, Juan, Wang, Jianming, Zhang, Tianliang, Xu, Dandan, Hu, Wenwei, Feng, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930565/
https://www.ncbi.nlm.nih.gov/pubmed/33681231
http://dx.doi.org/10.3389/fcell.2021.648808