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The Interplay Between Tumor Suppressor p53 and Hypoxia Signaling Pathways in Cancer
Hypoxia is a hallmark of solid tumors and plays a critical role in different steps of tumor progression, including proliferation, survival, angiogenesis, metastasis, metabolic reprogramming, and stemness of cancer cells. Activation of the hypoxia-inducible factor (HIF) signaling plays a critical rol...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930565/ https://www.ncbi.nlm.nih.gov/pubmed/33681231 http://dx.doi.org/10.3389/fcell.2021.648808 |