Exploring the Potential of Cytochrome P450 CYP109B1 Catalyzed Regio—and Stereoselective Steroid Hydroxylation

Cytochrome P450 enzyme CYP109B1 is a versatile biocatalyst exhibiting hydroxylation activities toward various substrates. However, the regio- and stereoselective steroid hydroxylation by CYP109B1 is far less explored. In this study, the oxidizing activity of CYP109B1 is reconstituted by coupling red...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaodong, Hu, Yun, Peng, Wei, Gao, Chenghua, Xing, Qiong, Wang, Binju, Li, Aitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930613/
https://www.ncbi.nlm.nih.gov/pubmed/33681151
http://dx.doi.org/10.3389/fchem.2021.649000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930613/
https://www.ncbi.nlm.nih.gov/pubmed/33681151
http://dx.doi.org/10.3389/fchem.2021.649000

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