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Exploring the Potential of Cytochrome P450 CYP109B1 Catalyzed Regio—and Stereoselective Steroid Hydroxylation
Cytochrome P450 enzyme CYP109B1 is a versatile biocatalyst exhibiting hydroxylation activities toward various substrates. However, the regio- and stereoselective steroid hydroxylation by CYP109B1 is far less explored. In this study, the oxidizing activity of CYP109B1 is reconstituted by coupling red...
Autores principales: | Zhang, Xiaodong, Hu, Yun, Peng, Wei, Gao, Chenghua, Xing, Qiong, Wang, Binju, Li, Aitao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7930613/ https://www.ncbi.nlm.nih.gov/pubmed/33681151 http://dx.doi.org/10.3389/fchem.2021.649000 |
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